Among the major areas of care fixated by people is their health. As such, advances in medicines are duly welcome and highly appreciated. Progress in research of various diseases and development of drugs to help curb them is always a good indicator. One such aspect of progress has been noted in liposomal formulation.
There has always existed the problem of ingested drugs being digested before reaching their intended target areas in the body. The process of these formulations was discovered as scientists were looking for a solution to this problem. In this solution, the drug would be closed in and protected by a layer of phospholipids and aqueous solution.
Liposomes bio structure is favorable. They are mainly aqueous at the core. This is close in by a layer of phospholipids. Various strains have different types of phospholipids they could be either natural or synthetically prepared in a laboratory. This provides an ideal state where both extremes of drugs can be safely transported, by either attaching to the liquid core or the lipid outer layers.
Researchers have found the process of formation of these compounds may be critical to their performance. They are formed when strands of phospholipids are put in water, and a given heat amount is directed to them. The composition of the formed liposomes is tested against that of this drug it is intended to carry, so as to determine compatibility and avoid destructive reactions.
Advances like these have led to researchers getting further progress in the field. The most famous result being an anthracycline drug known as Doxorubicin, developed specifically to curb the spread of various variations of cancer. It inserts strains of base RNA and DNA into the malignant cells, and also the topoisomerase enzyme in later stages. This actively inhibits the spread of the disease.
It is due to advances in the medical field that control of many diseases is not a reality. Terminal illnesses previously viewed as a death sentence are now controllable and some even treatable. Research on cancer and liposomes has led to development of anti-cancer drugs an their carriers. The development has brought about continuing tests and usage of doxorubicin, paclitaxel, cisplatin, lipoplatin, aroplatin among others.
The study of liposomes has also led to development of vaccines and various other treatments. Various diseases and medical conditions which previously had no cure can now be vaccinated against. Such developments have established Epaxal, a vaccine against Hepatitis A, and Inflexal V, a vaccine against several types of influenza. A vaccine known as Stimuvax against lighter forms of cancer is in the offing.
The use of liposomes as a carrier for dietary supplements is a newer idea that I undergoing further research. The idea is to use the same technique as the currently successful targeted drug delivery to deliver various supplements taken orally to specific areas in the body. This is however still undergoing research and testing. The use of liposomes in creation of various drugs and vaccines has led to a huge leap in terms of drug research and development. The process of the formulation has thus been lauded as wielding enormous potential for development of better medical solutions for a lot of persistent medical conditions.
There has always existed the problem of ingested drugs being digested before reaching their intended target areas in the body. The process of these formulations was discovered as scientists were looking for a solution to this problem. In this solution, the drug would be closed in and protected by a layer of phospholipids and aqueous solution.
Liposomes bio structure is favorable. They are mainly aqueous at the core. This is close in by a layer of phospholipids. Various strains have different types of phospholipids they could be either natural or synthetically prepared in a laboratory. This provides an ideal state where both extremes of drugs can be safely transported, by either attaching to the liquid core or the lipid outer layers.
Researchers have found the process of formation of these compounds may be critical to their performance. They are formed when strands of phospholipids are put in water, and a given heat amount is directed to them. The composition of the formed liposomes is tested against that of this drug it is intended to carry, so as to determine compatibility and avoid destructive reactions.
Advances like these have led to researchers getting further progress in the field. The most famous result being an anthracycline drug known as Doxorubicin, developed specifically to curb the spread of various variations of cancer. It inserts strains of base RNA and DNA into the malignant cells, and also the topoisomerase enzyme in later stages. This actively inhibits the spread of the disease.
It is due to advances in the medical field that control of many diseases is not a reality. Terminal illnesses previously viewed as a death sentence are now controllable and some even treatable. Research on cancer and liposomes has led to development of anti-cancer drugs an their carriers. The development has brought about continuing tests and usage of doxorubicin, paclitaxel, cisplatin, lipoplatin, aroplatin among others.
The study of liposomes has also led to development of vaccines and various other treatments. Various diseases and medical conditions which previously had no cure can now be vaccinated against. Such developments have established Epaxal, a vaccine against Hepatitis A, and Inflexal V, a vaccine against several types of influenza. A vaccine known as Stimuvax against lighter forms of cancer is in the offing.
The use of liposomes as a carrier for dietary supplements is a newer idea that I undergoing further research. The idea is to use the same technique as the currently successful targeted drug delivery to deliver various supplements taken orally to specific areas in the body. This is however still undergoing research and testing. The use of liposomes in creation of various drugs and vaccines has led to a huge leap in terms of drug research and development. The process of the formulation has thus been lauded as wielding enormous potential for development of better medical solutions for a lot of persistent medical conditions.
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